Scientist Cardio-Renal, Eye and Metabolic Diseases

Merck - South San Francisco, CA

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company - one that is ready to help create a healthier future for all of us. 

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you'll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career. 

Scientist - Cardio-Renal, Eye and Metabolic Diseases
South San Francisco, CA 
Job # RES001847

The Cardio-Metabolic Disease therapeutic area within Discovery Research at Merck is seeking to recruit a Scientist that is highly motivated to applying their skills towards the identification and development of novel targets to treat a broad array of cardio-renal, eye and metabolic diseases. However, the most important singular quality we are looking for is a drug hunter that seeks to put patients first as the front and central goal of their research. The location will be the preclinical research laboratories at our new state of the art facility in the South San Francisco Bay Area where you will be able to participate in a vibrant culture connecting leading academic and biotech research centers. Beyond local connections, you will also be able to supplement your research activities by taking advantage of the technologies and capabilities of the wider Merck network of sites in Boston, MA as well as NJ and PA. 

The individual will be expected to display independence in the laboratory in the design, plan, and execution of in vitro and/or in vivo experiments and provide scientific and technical input into the CMD portfolio.
The individual will be expected to balance work on multiple projects in support of our drug discovery and development goals at various stages of the preclinical research phase from target validation through to lead optimization.
The individual should be highly self-motivated, possess strong technical skills, have strong written and oral communication skills, and be able to work productively in a collaborative and cross functional team environment within and outside of the Merck Research Laboratories.
Relevant areas of training may include one or more of the following disease areas; heart failure, chronic kidney disease, diabetes, with particular focus on insulin resistance as well as diabetic complications, obesity as well as ocular diseases (spanning from cornea to the retina).

Job Requirements



Required: BA/BS in Pharmacology, Physiology, Pathology or related field
Preferred: MS in Pharmacology, Physiology, Pathology or related field

Required Experience: 

Minimum of (5) years of Industry and or Academic experience.
Molecular biology, Cellular biology, cell-based assay, and ex vivo sample processing and analysis.
Ophthalmology related work experience (i.e. in vitro or in vivo).
Demonstrated ability to perform standard procedures in live rodent models and to process specimens for analysis.

Preferred Experience: 

Surgical experience in one or more of the individual diseases listed above in the areas of Cardio-Renal, Eye and Metabolic Disease Research.
Experience in one or more of the following areas of drug discovery research: Target Identification & Validation, Lead Optimization High content imaging, flow cytometry, immunohistochemistry, mass spectrometry.
Experience with drug administration in rodents.

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South San Francisco, CA